Functionally suppressive CD8 T regulatory cells are increased in patients with multiple myeloma: a cause for immune impairment.

PLoS One · 2012 · PMC3496705 · PMID 23152910

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failed to reach statistical significanceno p-value reported

Also, similar observation was noticed between CD8 Treg cells and CD4/CD8 ratio but failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.