Metformin inhibits glutaminase activity and protects against hepatic encephalopathy.

PLoS One · 2012 · PMC3499552 · PMID 23166628

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showed a trendno p-value reported

HOMA-IR correlates with protein-C-reactive activity and patients receiving metformin showed a trend to lowering TNFr2 levels than non-metformin treated patients (data not shown).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.