highly significantP <1×10 −10
In these studies, a highly significant ( P <1×10 −10 ) association was detected for CDKAL1 , in accordance with the present study in Japanese.
In these studies, a highly significant ( P <1×10 −10 ) association was detected for CDKAL1 , in accordance with the present study in Japanese.
In accordance with the findings in mice, a nominally significant ( P <0.05) association between CDKAL1 rs4712523 and BMI was replicated in 2 Japanese general populations comprising 5,695 and 12,569 samples; the risk allele for type 2 diabetes was also associated with decreased BMI.