We found similar results than those with GRS1 and lifestyle factors, with the joint association between GRS2 and lifestyle factors being stronger although the P values for interaction failed to reach significance.
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Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.
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The sentences
We found that compared to participants with low GRS1 and no high risk factors for T2D, those with high GRS1 and three high risk factors had a higher risk of T2D (OR = 13.06; 95% CI: 8.65–19.72) but the interaction factor was of marginal significance.