The CD46-Jagged1 interaction is critical for human TH1 immunity.

Nat Immunol · 2012 · PMC3505834 · PMID 23086448

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showed a trendno p-value reported

Although all three patients showed a trend towards reduced CD25 upregulation and CD62L down-regulation upon CD3 and CD3+CD28 activation as well as a small memory T cell pool (CD4 + CD45RA − CD45RO + cells), these results were within the range of normal donor variation (data not shown).

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