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Interactions between serum vitamin D levels and vitamin D receptor gene FokI polymorphisms for renal function in patients with type 2 diabetes.

PLoS One · 2012 · PMC3514263 · PMID 23226566

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On the other hand, 25OHD and 1,25OHD levels of CKD stage 1∼2 in December tended to be higher than in other months, but differences did not reach statistical significance. 25OHD/1,25OHD, and eGFR Levels eGFR levels were compared with 25OHD ( Fig. 3A ) and 1,25OHD ( Fig. 3B ) levels. eGFR levels were in direct proportion to both 25OHD ( P <0.0001) and 1,25OHD levels ( P <0.0001), but had a stronger linearity for 1,25OHD (r = 0.73) than 25OHD (r = 0.22). 1,25OHD levels were positively associated with in Ca levels ( P <0.0001), whereas they were negatively associated with P levels ( P <0.0001) and iPTH levels ( P <0.0001).

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