For the DNA dose of 17.5 μg, the difference in peak mean bioluminescence signal using cationic MBs (2.6 ± 2.9 x 10 6 photons/sec/cm 2 /sr) versus neutral MBs (1.4 ± 1.3 x 10 6 photons/sec/cm 2 /sr) did not reach statistical significance ( P = 0.14).
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Ultrasound-mediated gene delivery with cationic versus neutral microbubbles: effect of DNA and microbubble dose on in vivo transfection efficiency.
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0.1400
0.1400