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Gonadotropin-releasing hormone receptor activates GTPase RhoA and inhibits cell invasion in the breast cancer cell line MDA-MB-231.

BMC Cancer · 2012 · PMC3518142 · PMID 23176180

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Although the amount of F-actin was higher in cells transfected with the GnRHR-DesK191 than in those transfected with the WT receptor, the difference did not reach statistical significance.

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