The influence of climatic conditions on the transmission dynamics of the 2009 A/H1N1 influenza pandemic in Chile.

Timing of pandemic onset The onset date of the first SARI hospitalization across Chilean regions was associated with population size, with more populous regions experiencing earlier pandemic onset than low population regions (Spearman rho = −0.61, P = 0.02), but this correlation did not reach statistical significance using A/H1N1-positive SARI hospitalizations (Spearman rho = −0.4, P = 0.14).

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The south–north gradient in peak timing observed in our study is consistent with a decreasing trend in the reproduction number in the same direction and is statistically associated with maximum temperature and specific humidity.

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