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Burden of acute otitis media in primary care pediatrics in Italy: a secondary data analysis from the Pedianet database.

BMC Pediatr · 2012 · PMC3519519 · PMID 23190626

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a negative trendno p-value reported
The long-term rates showed a negative trend (APC −4.6%; 95%CI: from −5.3 to −3.9%).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.