Increasing hippocampal estrogen receptor alpha levels via viral vectors increases MAP kinase activation and enhances memory in aging rats in the absence of ovarian estrogens.

PLoS One · 2012 · PMC3519866 · PMID 23240018

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0.0770

closest p · 1.5× alpha

0.0770

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nearly significantP = .077so close (0.05 < p ≤ 0.1)

Two-way ANOVA revealed a nearly significant effect of treatment (F (1,10) = 3.885, P = .077) indicating greater accuracy in the Lenti-ERα rats ( Figure 3A ).

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