The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age.

PLoS Pathog · 2012 · PMC3521721 · PMID 23271970

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did not reach statistical significanceno p-value reported

We did note a trend towards elevated frequencies of CMV- and EBV-specific CD8+ IFN-γ+ T cells in the middle-aged and aged cohorts relative to the young cohort, but this trend did not reach statistical significance ( Figures 2B–D ).

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