Although the decrease in the absolute amount of cytokine in the PRED group, as revealed by the IOD index, did not reach statistical significance ( p = 0.195, Figure 5 compared with the CBDL group, when transformed into the mean density (ratio between the IOD and positive area), a significant decrease was revealed ( p = 0.001, Figure 6 .
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Effects of the administration of pentoxifylline and prednisolone on the evolution of portal fibrogenesis secondary to biliary obstruction in growing animals: immunohistochemical analysis of the expression of TGF-β and VEGF.
1
0.1950
0.1950