TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipid-induced inflammation and insulin resistance in muscle cells.

Biosci Rep · 2012 · PMC3522475 · PMID 23050932

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did not reach statistical significanceno p-value reported

There was also a tendency for reduced (approximately 18%) insulin-stimulated GSK-3α/β phosphorylation; however, this did not reach statistical significance ( Figure 5 B).

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