IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse.

BMC Musculoskelet Disord · 2012 · PMC3522537 · PMID 22716658

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

did not reach statistical significanceP = 0.055so close (0.05 < p ≤ 0.1)

Antibody treatment resulted in an 11 % greater strength increase (hindlimb) in IL-6r mAb treated mdx mice compared to Kh-5 treated mdx mice, though this did not reach statistical significance (6.5 ± 0.2 N/g versus 5.7 ± 0.3 N/g, P = 0.055).

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