Long CAG repeat sequence and protein expression of androgen receptor considered as prognostic indicators in male breast carcinoma.

This study revealed the following important findings: (a) there was a significant difference in the CAG repeat lengths between MBC patients and controls; (b) long CAG repeat lengths were more common in patients than controls and there was a strong trend toward short CAG repeat lengths being more prevalent in controls than in cases; (c) long CAG repeat sequence presented at the T2-4 stage compared with short CAG repeat sequence in MBC patients but did not differ with respect to other clinicopathological features; (d) there was a significant difference by ER and PR status regarding AR expression in the MBC patients; (e) the presence of long CAG repeat sequence and AR-positive expression were associated with shorter survival of MBC patients.

also in 5,725 other papers