Note that instead of the traditional cutoff P -value 0.05, we used FDR < 0.2 such that marginally significant pathways would not be overlooked and an appropriate number of pathways could be derived.
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Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer.
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SRT found 3 nominally significant pathways using tier one criterion, but none passed the multiple testing correction using tier two criterion (Table 3 ).