While no association was observed between ALDH1A1*2 and alcohol dependence, there was a nominally significant difference in ALDH1A1*3 allelic frequency between alcoholics (6 per cent) and controls (0), and the ALDH1A1*3 polymorphism resulted in reduced ALDH1A1 expression.
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The role of aldehyde dehydrogenase-1 (ALDH1A1) polymorphisms in harmful alcohol consumption in a Finnish population.
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