A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers.

PLoS One · 2012 · PMC3527451 · PMID 23284689

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showed a trendno p-value reported

31P MRS, MRI and Maximal Aerobic Capacity Test SRT2104 0.5 g/day and 2.0 g/day showed a trend for a decrease in half-time for recovery of the calculated adenosine diphosphate (ADP) concentration (ADP T 1/2 ) values after exercise, on day 27 relative to baseline ( Table S1 ).

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