Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress.

Moreover, when we determined the residual metabolic activity of the cta1 Δ/Δ mutant after confrontation with neutrophils, we found that although this mutant showed a trend towards decreased survival, the susceptibility in the killing assay was not significantly increased ( Fig. 5A ).

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