Barely Significant
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Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43.

PLoS One · 2012 · PMC3530536 · PMID 23300771

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a clear trendno p-value reported
3B, b ), and D247G showed a clear trend of higher insolubility than that of WT.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.