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Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retina.

PLoS One · 2013 · PMC3534656 · PMID 23301080

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A small decrease of 19% in CDK1 expression levels could already be noticed after a 12 h incubation of the explants with LY, although the effect of the inhibitor did not reach statistical significance at this time point.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.