Factors determining the occurrence of submicroscopic malaria infections and their relevance for control.

Indeed, there was a borderline significant association for a smaller effect of age in higher transmission settings ( P =0.055).

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Nevertheless, the public health importance of low-density infections may be significant, as experiments have shown that mosquitoes feeding on individuals who are parasite-negative by microscopy can become infected with malaria 7 , 8 .

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Parasite densities assessed by microscopy show a clear trend of increasing with increasing transmission intensity ( Fig. 2b ).

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