Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease.

Conditional logistic regression of the combined dataset demonstrated nominally significant association of JIA with lower methylation at CpG_9, such that a 1% increase in methylation equates to a 6% decrease in risk of being a JIA case (OR = 0.94, 95% CI: 0.87, 1.00; p = 0.064).

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