The role of tobacco, alcohol, and obesity in neoplastic progression to esophageal adenocarcinoma: a prospective study of Barrett's esophagus.

PLoS One · 2013 · PMC3536789 · PMID 23300966

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a significant trendno p-value reported

We observed a significant trend (p trend = 0.01) between increasing WHR and EA risk in univariate analyses, but adjustment for the confounding effects of age, gender, smoking and NSAID attenuated the association substantially such that the association was no longer statistically significant (p trend = 0.16) (HR = 1.48; 95%CI 0.60–3.61, comparing extreme quartiles).

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