However, for the combination of diuretics with NSAIDs, we found an overall effect modification by duration of use, with the highest risk observed in the first 30 days of use, although that estimate did not reach statistical significance (rate ratio 1.46, 0.96 to 2.24).
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Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal anti-inflammatory drugs and risk of acute kidney injury: nested case-control study.
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