The gene expression of Prl and the prolactin regulatory element-binding protein Preb ( 32 ) showed an increase in hCGβ+ females, and there was a tendency for a lower expression after cabergoline treatment, but the difference did not reach statistical significance ( Fig. 2 , G and H).
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Short-term pharmacological suppression of the hyperprolactinemia of infertile hCG-overproducing female mice persistently restores their fertility.
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