Modulation of cough response by sensory inputs from the nose - role of trigeminal TRPA1 versus TRPM8 channels.

No considerable drop of FEV 1 or FVC was detected after nasal TRPA1 and TRPM8 relevant challenges (Table 1 ). Cough reflex sensitivity and cumulative cough count for TRPA1 line Data obtained for C2 and C5 were shifted from baseline and vehicle values, however, difference did not reach statistical significance.

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