ENU mutagenesis reveals that Notchless homolog 1 (Drosophila) affects Cdkn1a and several members of the Wnt pathway during murine pre-implantation development.

However only Cdkn1a , which was upregulated by 4.7 fold in mutant samples (Figure 4 ) (p = 1.94X10 -8 ), was statistically significant using post hoc tests corrected for multiple comparisons (accepting p < 0.000769); none of the other genes approached significance, even at an uncorrected threshold of p < 0.05.

also in 8,237 other papers