Effects of pharmacologic therapy on health-related quality of life in elderly patients with atrial fibrillation: a systematic review of randomized and nonrandomized trials.

65 Rhythm control patients were more likely to be hospitalized for arrhythmias and rate control patients were more likely to be hospitalized for heart failure, but the difference in total number of clinical events between these patients did not reach statistical significance at 1-year follow-up in RECORD-AF. 65 In the AFFECTS registry, there were too few deaths and cardiovascular-related events for a meaningful comparison between rhythm control and rate control strategies. 67 Data obtained from RECORD-AF and AFFECTS provide a “real-world” look at a physician’s choice of treatment for the management of patients with AF.

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