Barely Significant
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Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.

Clin Infect Dis · 2013 · PMC3563392 · PMID 23175556

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a slight trendno p-value reported
There was a slight trend that splitting the AS dose in a twice-daily administration did accelerate parasite clearance in artemisinin-resistant malaria in Pailin, but this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.