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Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage.

Carcinogenesis · 2013 · PMC3564441 · PMID 23125222

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However, although flow cytometry analysis of cells stained for phospho-histone H3 (pH3) confirmed the reduction in mitotic cells following caffeine treatment, the decrease observed in response to DBH did not reach statistical significance ( Figure 5F ).

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