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A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis.

PLoS One · 2013 · PMC3568129 · PMID 23408987

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a strong trendno p-value reported
In the acute phase of post-traumatic sepsis, we recorded a distinct upregulation of PAI-1 gene expression in the liver (also a strong trend to increases in the LCVC).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.