Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf.

EMBO Mol Med · 2013 · PMC3569658 · PMID 23180554

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BM analysis at earlier time points was complicated by highly variable responses, in part due to large numbers of dying recipient BM cells and low numbers of donor-derived LSK cells detectable by flow cytometry, but consistently showed a trend that early engraftment was facilitated by loss of Bim or overexpression of Bcl-2 (Supporting Information Fig 1C ).

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