Matrix metalloproteinase 9 and cellular fibronectin plasma concentrations are predictors of the composite endpoint of length of stay and death in the intensive care unit after severe traumatic brain injury.

Relationship between MMP-9, c-Fn, fGCS and the composite endpoint Statistically lower fGCS ( p = 0.03, n = 49) and higher maximal late c-Fn concentration (+123%, p = 0.007, n = 46) as well as a strong trend toward higher maximal early MMP-9 concentration (+50%, p = 0.06, n = 43) were observed in patients dying or staying for 10 days or more in the ICU as compared to patients who were alive and who left the ICU before 10 days (Table 3 ).

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