Functional network endophenotypes unravel the effects of apolipoprotein E epsilon 4 in middle-aged adults.

There were no statistical significant differences in age, gender, education, cognitive and depressive symptom scores ( p >0.05) between groups, although APOE-ε4 carriers showed a trend toward lower RAVLT-DR (p = 0.10) and Digit Span Test ( p = 0.07) scores, when compared to non ε4 carriers ( Table 1 ).

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