High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring.

Mammary tumour incidence was higher in both HF F2 outcross groups (HF (female)×Con (male): 68%; and Con (female)×HF (male): 69%) compared with controls (50%), but did not reach statistical significance ( P =0.44, log-rank test; Fig. 1g ).

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