Reduced syncytin-1 expression levels in placental syndromes correlates with epigenetic hypermethylation of the ERVW-1 promoter region.

PLoS One · 2013 · PMC3573012 · PMID 23457515

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No significant changes between control and pathological CTs could be shown; however CTs isolated from HELLP/IUGR placentae showed a trend towards a higher methylated profile (23%) compared to control (13%) ( Fig. 1 ; Table S1 ).

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