Morphological and metabolic changes in the nigro-striatal pathway of synthetic proteasome inhibitor (PSI)-treated rats: a MRI and MRS study.

PLoS One · 2013 · PMC3576393 · PMID 23431380

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did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Dopamine and Dopamine Metabolite Level HPCL Measurement Decreased levels of DA in the striatum were found at 6 weeks after the end of PSI treatment as compared to controls (p = 0.02, Figure 6 , panel B ); a decrement was also observed in the level of the dopamine metabolite DOPAC in the PSI-treated rats, but did not reach statistical significance (p = 0.07).

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