nominally significantP = 0.045
A large number of preplanned exploratory analyses were performed in the PLATO trial, and a nominally significant treatment interaction for geographic region ( P = 0.045) was observed.
A large number of preplanned exploratory analyses were performed in the PLATO trial, and a nominally significant treatment interaction for geographic region ( P = 0.045) was observed.
Clopidogrel was associated with a nonsignificant trend of better outcome for North America alone, while ticagrelor was associated with better outcome in the other regions combined ( 11 ).