Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.

BMC Med Genet · 2013 · PMC3583714 · PMID 23394302

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hedged sentences

0.0010

closest p · 0.0× alpha

0.0100

boldest claim

The sentences

nominally significantp = 0.001actually significant

Both SNPs remained nominally significant in dichotomized analyses for the presence of any CAC (odds ratio rs1537373 (OR) = 1.19; 95% CI = 1.07-1.31; p = 0.001 and OR rs9349379 = 1.26; 95% CI = 1.14-1.40); p = 1.5x10 -5 ).

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marginally significantp = 0.01actually significant

However, only rs10965219 showed a marginally significant genotype and gender interaction (after Bonferroni correction) (Beta rs10965219xgender = −0.23; 95% CI = −0.4 to −0.05); p = 0.01).

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