Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.

Although the observed trends did not reach statistical significance by Wilcoxon Two-Sample analysis, similar findings were also observed in the examination of trabecular bone density (not shown).

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Since all outcomes were marginally or highly significant overall, pair wise comparisons between groups were done via Wilcoxon Two-Sample tests, to identify outcomes that were significantly different between treatments.

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