No sex-related difference was apparent in any of the pharmacokinetic or binding parameters (e.g. serum clearances in male and female subjects were 0.186 and 0.176 L/day, respectively). 5.4 Patient Population Pharmacokinetic parameters were generally comparable across the healthy subjects and patient populations.
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Pharmacokinetic and pharmacodynamic properties of canakinumab, a human anti-interleukin-1β monoclonal antibody.
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