Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function.

Although CES1 mRNA level was not significantly associated with 120-min OGTT glucose level ( Table 2 ), we found a borderline significant association ( P = 0.057) between the levels of OGTT glucose and CES1 mRNA after adjustment for age, sex and BMI ( Figure 2 ).

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Although a previous small-sized study also found CES1 mRNA expression level in visceral adipose tissue to be inversely associated with age, the association for subcutaneous adipose tissue in this study did not reach statistical significance.

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