Influence of in vitro IL-2 or IL-15 alone or in combination with Hsp-70-derived 14-mer peptide (TKD) on the expression of NK cell activatory and inhibitory receptors.

Mediators Inflamm · 2013 · PMC3588175 · PMID 23476104

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nearly significantno p-value reported

Analysis of Cell Surface Expression of NK Cell Receptors in Relation to IL-2 and TKD Peptide Treatment Compared to unstimulated cells, low-dose IL-2 alone and the combination of IL-2/TKD peptide induced a significant or nearly significant upregulation of CD94, most NK cell activatory receptors such as NKG2D, NKp44, NKp30, KIR2DL4, DNAM-1, LAMP1, and NK cell inhibitory receptors like NKG2A and NKR-P1A ( Figure 1(a) ).

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