Barely Significant
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A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis.

PLoS One · 2013 · PMC3591368 · PMID 23505555

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Although we observed a trend for development of dominant bile duct stenosis (p = 0.167) in I148M patients, this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.