Metabolic shifts induced by fatty acid synthase inhibitor orlistat in non-small cell lung carcinoma cells provide novel pharmacodynamic biomarkers for positron emission tomography and magnetic resonance spectroscopy.

Mol Imaging Biol · 2013 · PMC3591534 · PMID 22886728

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

Orlistat treatment inhibited FASN activity in H3255 cells but did not reach statistical significance ( p = 0.06).

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