Factors of influence on acute skin toxicity of breast cancer patients treated with standard three-dimensional conformal radiotherapy (3D-CRT) after breast conserving surgery (BCS).

In addition to our data, there are a few studies that did not find a significant correlation between chemotherapy and increased skin toxicity [ 5 , 13 ], on the other hand other published analyses showed a trend to increased higher grade skin toxicities after chemotherapy [ 7 , 22 ], at which patients treated with anthracyclines seem to develop more skin reactions after EBRT [ 30 ].

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Larger T-stages and treatment with aromatase inhibitors showed a positive trend on the development of higher grade erythema.

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