Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.

PLoS One · 2013 · PMC3602591 · PMID 23527068

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

However, when enhanced by FUS, EB deposition in the brain tumor region further increased by 2.1 fold (7.92±1.36 μM), but did not reach statistical significance (p = 0.09).

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