Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.

In addition to LTβ, several pro-inflammatory cytokines, notably TNFα, IL6 and Il1β ( Figure S3 ) were mildly, but significantly increased in HCV-related tumors, while changes of interferons α and β expression ( Figure S4 ) did not reach statistical significance.

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